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Posted On July 19, 2021
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Differences in baseline performance could also clarify the results of Repantis et al.’s systematic review of the effects of modafinil in healthy subjects. They found a moderate positive effect for a single dose administration of modafinil on reaction time, divided, sustained and selective attention. However, Battleday and Brem suggested that some of the cognitive tests employed might not have been sensitive enough to find improvements in healthy, non-sleep deprived adults. Repantis et al. acknowledged that the cognitively improving ramifications of modafinil are greater in sleep-deprived individuals which the consequences of CEDs depend, to a certain degree, with an individual’s baseline performance.
According to one review, amphetamine can be prescribed to people with a brief history of abuse so long as appropriate medication controls are employed, such as requiring daily pick-ups of the medication from the prescribing physician. of the drug being excreted unchanged at normal urinary pH. When the urinary pH is basic, amphetamine is its free base form, so less is excreted. When urine pH is abnormal, the urinary recovery of amphetamine may range between a low of 1% to a higher of 75%, depending mostly upon whether urine is too basic or acidic, respectively. Following oral administration, amphetamine appears in urine within 3 hours. Roughly 90% of ingested amphetamine is eliminated 3 days following the last oral dose.
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